Research Groups
CRUK Scotland Institute publications are available as open access articles at Europe PubMed Central.
Research groups at the Scotland Institute are placing a particular emphasis on the following key themes:
- Cancer vulnerabilities caused by energetic stress and aberrant metabolism;
- Interplay between the tumour microenvironment, metastasis and recurrence; and
- Biology of early disease, aimed at developing a ‘precision prevention’ approach.

Models of Advanced Prostate Cancer
Group Leader:
Prof Imran Ahmad

Liver Cancer, Disease and Regeneration
Group Leader:
Prof Tom Bird

In Vivo Cancer Biology
Group Leader:
Prof Karen Blyth

Epithelial Polarity
Group Leader:
Prof David Bryant

RNA and Translational Control in Cancer
Group Leader:
Prof Martin Bushell

Biology of Therapeutics
Group Leader:
Prof Ross Cagan

Leukocyte Dynamics
Group Leader:
Prof Leo Carlin

Immune Cells and Metastasis
Group Leader:
Prof Seth Coffelt

Local and Systemic Functions of the Intestine in Health and Disease
Group Leader:
Prof Julia Cordero

Gene Regulation
Group Leader:
Prof Vicky Cowling

Cancer Systems Biology and Tumour Evolution
Group Leader:
Prof Ramanuj DasGupta

Metastasis and Circadian Rhythm
Group Leader:
Dr Zoi Diamantopoulou

Phenotypic Plasticity in Colorectal Cancer
Group Leader:
Prof Philip Dunne

Molecular Subtypes and the Host in Pancreatic Cancer
Group Leader:
Dr Fieke Froeling

Integrative Modelling
Group Leader:
Dr Xiao Fu

Mitochondrial Oncogenetics
Group Leader:
Prof Payam Gammage

Mitochondrial Genetics in Cancer
Group Leader:
Prof Laura Greaves

Childhood Leukaemia
Group Leader:
Prof Chris Halsey

Ubiquitin Signalling
Group Leader:
Prof Danny Huang

Growth Factor Signalling and Squamous Cancer
Group Leader:
Prof Gareth Inman

Deep Phenotyping of Solid Tumours
Group Leader:
Prof John Le Quesne

Prostate Cancer Biology
Group Leader:
Prof Hing Leung

Molecular Imaging
Group Leader:
Prof David Lewis

Mitochondrial Reprogramming in Cancer
Group Leader:
Dr Tom MacVicar

Cell State Control of Oncogenic Signalling
Group Leader:
Dr Ralitsa Madsen

Microbial and Metabolic Immune Modulation
Group Leader:
Dr Kendle Maslowski

Computational Biology
Group Leader:
Prof Crispin Miller

Preclinical Pancreatic Cancer
Group Leader:
Prof Jen Morton

Oncogene-Induced Vulnerabilities
Group Leader:
Prof Daniel J Murphy

Integrin Cell Biology
Group Leader:
Prof Jim Norman

Epithelial Homeostasis and Immune Regulation at Barrier Surfaces
Group Leader:
Prof Srikala Raghavan

Transcriptional and Epigenetic Control in Cancer
Group Leader:
Dr Shalini Rao

Clonal Dynamics in Cancer
Group Leader:
Dr Alex Raven

Immune Priming and the Tumour Microenvironment
Group Leader:
Prof Ed Roberts

Tumour Cell Death
Group Leader:
Prof Kevin Ryan

Colorectal Cancer and Wnt Signalling
Group Leader:
Prof Owen Sansom

Advanced Colorectal Cancer
Group Leader:
Dr Colin Steele

Mitochondria and Cell Death
Group Leader:
Prof Stephen Tait

Metabolic Crosstalk in Cancer
Group Leader:
Dr Johan Vande Voorde

AI for Cancer Research
Group Leader:
Dr Ke Yuan

