Postdoctoral Research Scientist - Professor Danny Huang
Professor Danny Huang
Ubiquitin Signalling Laboratory
Salary: from £37,000 to £42,893 subject to experience, plus relocation allowance and visa costs if required.
Contract term: Fixed up to 6 years, subject to successful review at Year 3.
About us
The CRUK Scotland Institute where the lab is based is a world leading cancer research institute, situated in the vibrant city of Glasgow in Scotland and hosting approximately 60 postdoctoral researcher scientists at any one time. It has an excellent reputation for fundamental cancer research, including world-class metabolism studies and renowned in vivo modelling of tumour growth and metastasis.
Project outline
We are seeking for a highly motivated postdoctoral fellow to join the laboratory of Prof. Danny Huang. This MRC-funded position focuses on the characterisation of an oncogenic protein and PROTAC-mediated degradation, in collaboration with Dr David France at the University of Glasgow.
The Huang Lab has a strong interest in understanding the structures, mechanisms and functions of ubiquitin ligases and how their deregulation contributes to cancer. The group has the expertise in recombinant protein expression and purification, structural characterisation of protein complexes, and mechanistic analyses using both biochemical and cell-based approaches. Based at the CRUK Scotland Institute, we benefit from a collaborative environment and work closely with core facilities and other research groups to access advanced techniques, including proteomics, RNA sequencing analysis, advanced microscopy, and genetic mouse models. The candidate will have access to these technologies to support the development of the project.
The ideal candidate will hold (or close to completing) a PhD in biochemistry, biology, or a related field, with strong experience in molecular and cell biology, demonstrated by at least one first-author publication. Prior experience with PROTAC characterisation or research in the ubiquitin pathway is highly desirable. The successful applicant will receive training in recombinant protein purification and biophysical and structural characterisation where necessary. They will be expected to take active role in experimental design, data analysis, coordination of collaborative meetings with the France group, and dissemination of results through publications and presentations.
For informal enquiries please contact Professor Danny Huang (d.huang@crukscotlandinstitute.ac.uk)
Postdoc support
Postdocs are key members of our research community, and we offer them a range of opportunities to train and develop as researchers while they are with us:
- Exciting, innovative cancer research projects in state-of-the art labs
- A highly collaborative and interactive research environment
- Access to and training in key advanced technologies, for example imaging and in vivo modelling
- A mentor enabling scheme to aid personal and professional development
- A rich programme of scientific exchange through seminars, workshops and meetings.
- Support to make fellowship and small grant applications, including during their transition to their next position
- Guidance and mentoring to compete for an independent scientist position as well as a multitude of other career options, including in industry.
- A highly engaged postdoc forum providing peer support, training, careers advice and regular social events
Equality, Diversity and Inclusion
Our overarching research ethos at the Institute is about excellence, honesty, openness, accountability and integrity. The diversity of our staff and students is also what makes the Institute such a vibrant place to work and advance discoveries in cancer research. Family friendly policies, our collaborative ethos, a focus on good mental health and well-being and opportunities for all help to create an enjoyable and inclusive workplace where your voice matters.
The Institute is also committed to increasing the number of female scientists at the postdoc level and beyond and encourages female applicants to apply. We have recently introduced a highly attractive maternity policy which provides 12-18 months support and funding for postdocs wishing to take time off to spend with their children amongst other family friendly policies.
Employee Benefits
- Competitive salary
- 40.5 days annual leave including bank holidays (FTE)
- Defined contribution pension scheme
- Free life assurance scheme
- Employee Assistance Programme
- Interest free season ticket loans
- Additional maternity pay for 6 months at full salary
- Shared parental leave including up to 6 weeks paid at full salary
- Cycle to work scheme saving tax and NI on cycle purchase and spreading repayments over up to 12 months
- Access to employee benefit schemes with discounts on supermarkets, cinema, travel and much more.
- On-site secure parking
Closing Date: 08 August 2025
