Prof Imran Ahmad - Models of Advanced Prostate Cancer

Professor of Urological Oncology


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Prostate cancer is a leading cause of cancer mortality in men in the western world. Identifying and understanding the pathways that drive advanced and treatment-resistant prostate cancer will provide important information that will allow prognostication and individualised patient treatments.

Androgens have been found to be important for prostate cancer progression and androgen deprivation therapy is usually effective at initially controlling the disease. In many cases, however, there is a recurrent castration-resistant phase, for which there is no effective treatment.

My current research interest is in understanding the mechanisms of treatment-resistance in advanced prostate cancer. Work in my laboratory uses state-of-the-art in vivo models in conjunction with patient samples to interrogate the disease processes in advanced and treatment-resistant prostate cancer. This work will help to provide information on drivers of prostate cancer progression and to identify novel biomarkers of disease and/or drug targets to treat the disease.

As an Honorary Consultant Urological Surgeon based at the Queen Elizabeth University Hospital in Glasgow, I have a special interest in robotic surgery for advanced prostate and bladder cancer. I have successfully set up and trained members of the Robotic Pelvic Cancer Service in the West of Scotland. As a partnership between NHS Greater Glasgow & Clyde and the University of Glasgow, the service has delivered several practice-changing clinical surgical trials over the last 5-years.

Starter Grant for Clinical Lecturers awardee

Prof Imran Ahmad explains how a Starter Grant from the Academy of Medical Sciences allowed him to continue his research following his PhD. Click here to read the interview.